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DOC (Denominazione di Origine Controllata, "controlled designation of origin") is Italy's main tier of geographically defined, rule-governed wine production, sitting below DOCG and above IGT and Vino da Tavola in the country's four-tier pyramid established by a 1963 law (modeled on France's AOC system) and later aligned with EU-wide DOP/PDO rules.

DOC rules specify the permitted grape varieties, maximum yields, minimum alcohol levels, and aging requirements for wines from a defined zone.

There are several hundred DOCs across Italy — more numerous than DOCGs — ranging from broad regional appellations to small, specific zones.